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Se is known to contribute to several crucial physiological functions in mammals: antioxidant defense, fertility, thyroid hormone metabolism, and immune response (Hadaszadeh and Beggs, 2006

These findings indicate that Epitalons effects extend beyond simply boosting melatonin output, acting as a true circadian regulator capable of re-entraining disrupted biological rhythms in aging humans

Riezzo I, Cerretani D, Fiore C, Bello S, Centini F, DErrico S, Fiaschi AI, Giorgi G, Neri M, Pomara C, Turillazzi E, Fineschi V (2010) Enzymaticnonenzymatic cellular antioxidant defense systems response and immunohistochemical detection of MDMA, VMAT2, HSP70, and apoptosis as biomarkers for MDMA (ecstasy) neurotoxicity

J Neurosci 13: 16761687