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The widely repeated claim that Dihexa is "seven orders of magnitude more potent than BDNF" originates from that flagged McCoy paper and reflects an assay-specific in-vitro spine-density measurement picomolar Dihexa versus nanomolar BDNF in one assay not a millions-fold advantage in a living brain
Presented for research literature review only Manna D et al
Understanding the general peptide safety landscape helps put these results in context
A review on various uses of N-acetyl cysteine
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