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This mechanism reduces daily caloric intake naturallywithout requiring extreme willpower or restrictive dietingmaking sustainable weight loss more achievable for most patients
Semaglutide (2.4 mg once weekly) produced weight loss of up to 15.7% after 68 weeks in patients taking antidepressants compared with placebo
These insights underline the importance of setting realistic expectations with patients about both the potential benefits and limitations of GLP-1R agonists for weight management
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