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Regulation and quality control are vital too
Preclinical studies demonstrate that DSIP can alter pain threshold responses, with observed effects that are not reversed by opioid receptor antagonists such as naloxone, suggesting involvement of non-opioid or indirect neuromodulatory pathways [7]
The result: no evidence of causation
doi: 10.1016/J.WAOJOU.2021.100519 141 JamesEAKwokWW
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