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Similar to the transcriptomic changes observed in the hypothalamus, we found that the conjugate prompted transcriptional patterns enriched for functional terms associated with synaptic transmission, including postsynaptic specialization and neuron-to-neuron synapse in the brainstem (Extended Data Fig
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DISCUSSION 28 For instance, one study reported that among patients with inadequate bowel preparation, adenomas were missed in 47% of cases, particularly when the BBPS score was below 5, compared with 21% in those with excellent preparation
REDEFINE 2 adults with type 2 diabetes GI events were reported in 72.5% of CagriSema participants vs 34.4% on placebo
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