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Regulatory status Injectable GHK-Cu is not FDA-approved for any condition
A 2% serum through needled skin delivers the equivalent of 20% on intact skin
When to increase dose Consider increasing if: Minimal response after 4-6 weeks at current dose No side effects at current dose Current dose below the higher end of recommended range Goals not being met with conservative approach Increase gradually, typically by 25-50% at a time
Complexation using other ligands can also be explored but GHK is commonly used in cosmetics with properties such as the stimulation of collagen synthesis, chemotaxis, anti-stinging effects and others 47
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