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Unlike some medications that induce or inhibit cytochrome P450 enzymes, tirzepatide does not appear to affect the metabolic pathways responsible for breaking down contraceptive hormones
however, there is little data regarding glucagon-like peptide-1 receptor agonist in overdose
Newer agents such as tirzepatide (a dual GIP/GLP-1 receptor agonist) may offer different tolerability profiles, though gastrointestinal effects remain common and availability on the NHS may be limited pending NICE appraisal and local commissioning decisions
The LEAD clinical trials, which began in 2006 and included thousands of participants worldwide, demonstrated liraglutides ability to improve glycemic control and promote weight loss (35)
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