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The risk of gastrointestinal bleeding with naproxen is increased in those taking anticoagulants, antiplatelets, SSRIs/SNRIs, or corticosteroids, and in those aged over 65 or with a history of peptic ulcer disease
Pelin Cengiz F, Emiroglu N, Gulsel Bahali A, Su O, Onsun N
Figure 2 More recently, a multiple hits theory has been proposed, with the addition of other pathogenic factors in NAFLD development: low-grade chronic inflammation, genetic and epigenetic mutations, and intestinal microbiota
however, the incidence of acute gallbladder disease was greater in patients treated with Saxenda than with placebo even after accounting for the degree of weight loss
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