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The table treats PCOS and other fertility diagnoses as a factor that can shift the risk-benefit balance, since those conditions affect weight and ovulation at the same time

For the GSTO1 C4-10 complex, GSTO1 (2.66 mg ml 1 ) was incubated in a 1:1.5 molar ratio with C4-10 for 24 h at 4 C then concentrated to 26.2 mg ml 1

Whilst some adjustment period is expected, ongoing severe symptoms may indicate that the medication dose needs reviewing or that an alternative treatment approach should be considered

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