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Excretion Pathways Limited data on combined excretion indicates[21]: Primarily renal elimination of peptide fragments from all components Hepatic metabolism contributes to overall clearance Copper recycling through normal physiological pathways (GHK-Cu component) No evidence of accumulation in chronic dosing studies of individual components BPC-157 detectable in urine for up to 4 days

The generated HA fragments face two metabolic fates in the tissue microenvironment, 1

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