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Oral PUVA is now no longer preferred due to various adverse effects associated with oral psoralens, such as gastralgia, nausea, risk of severe generalized phototoxicity, and photocarcinogenesis
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In people with T2D, retatrutide (0.5 to 12 mg) led to substantial reductions in bodyweight and HbA1c compared to both placebo and dulaglutide 1.5 mg in a phase 2 trial [67]
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