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It is not known if RYBELSUS will cause thyroid tumors or a type of thyroid cancer called medullary thyroid carcinoma (MTC) in people Do not use RYBELSUS if: you or any of your family have ever had MTC, or if you have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) you have had a serious allergic reaction to semaglutide or any of the ingredients in RYBELSUS Before using RYBELSUS , tell your healthcare provider if you have any other medical conditions, including if you: have or have had problems with your pancreas or kidneys have a history of vision problems related to your diabetes are scheduled to have surgery or other procedures that use anesthesia or deep sleepiness (deep sedation) are pregnant or plan to become pregnant

2 CagriSema is not approved in the US or EU

This applies whether you are moving: from Wegovy (semaglutide) to Mounjaro (tirzepatide) , or from Mounjaro (tirzepatide) to Wegovy (semaglutide) This balances safety and practicality: it gives sufficient time for most of the prior drugs activity to decrease, helping to reduce the risk of overlapping effects and side effects

For manufacturers, this presents a dilemma