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2023 Dec 29;102(52):e36730
Cons of orforglipron At the highest (36mg) dose in ACHIEVE-1, 8% of trial participants discontinued usage owing to adverse events, with vomiting and nausea reported in 14% and 16% of participants respectively
This does make me want to dive in the data and see if I can develop hypotheses regarding the scale and durability of the weight loss after cessation of treatment, because that seems to be the next big battleground, but thats a story for another blog post
Proper medication management is crucial to avoid the risks associated with inadequate treatment
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