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The offer followed shortly after Metsera struck a deal to sell itself to Novos rival, Pfizer, that was worth up to $7.3 billion (which Metsera can still get out of)
Such a non-protein cofactor is known as a "prosthetic group." R -lipoic acid functions as a prosthetic group for the biological activity of the following multienzyme complexes: The glycine cleavage system that catalyzes the decarboxylation of glycine coupled with the addition of a methylene group (-CH 2 ) to tetrahydrofolate to form 5,10-methylene tetrahydrofolate, an important cofactor in the synthesis of nucleic acids ( Figure 3 )
Lyophilized storage at -80C is preferred for long-term stability
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