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The colonic endocrine hormone PYY decreased following Satb2 deletion or during colonic mucosal injury The colonic mucosa harbors diverse enteroendocrine cells with indistinct morphologies, including enterochromaffin cells (producing 5-HT), D cells (producing SST), and L cells (producing GLP-1 and PYY)
This has implications for drug metabolism that deserve their own dedicated section later in this guide
It communicates with your brain to reduce appetite, tells your liver to slow glucose production, and slows gastric emptying so you feel full longer
Here are the sites recommended for Ozempic, Wegovy, and similar medications: Abdomen (stomach area): The most common and versatile site
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