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Marginal deficiency Although frank vitamin E deficiency is rare, marginal intake of vitamin E may be relatively common

Stav K, Beberashvili I, Lindner A et al: Predictors of response to intravesical dimethyl-sulfoxide cocktail in patients with interstitial cystitis

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It does this by acting as a selective agonist at the GHSR-1a receptor , the same receptor that the hunger hormone ghrelin normally activates