tirzepatide moa vs semaglutide Tirzepatide: Complete Comparison (2026) Tirzepatide vs Semaglutide: Weight Loss,

If something changes, your provider is on site to take a look

it is available only within authorised clinical trials via programmes such as the TRIUMPH Phase 3 study

report right upper quadrant pain to your GP or trial clinician Diabetic retinopathy worsening: Seek urgent ophthalmic review if you experience sudden changes in vision Hypoglycaemia: More relevant when retatrutide is used alongside insulin or sulphonylureas Injection site reactions: Persistent lumps, pain, or skin changes at injection sites should be assessed by a clinician When to seek help: Call 999 for severe chest pain, difficulty breathing, signs of severe dehydration (collapse, confusion), or suspected anaphylaxis Contact NHS 111 or your GP for persistent vomiting or diarrhoea, suspected pancreatitis, or any new or worsening symptoms that concern you There is currently no official MHRA safety profile for retatrutide, as it remains unlicensed

Common side effects include: Most side effects are mild and temporary, often improving as your body gets used to the medication