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The influence of Glutamate and GABA on tracer penetration into parenchyma is AQP4-dependent Paravascular movement of CSF and ISF is reported to be driven by arterial pulsation and facilitated by an astroglial AQP4 water channel
Particularly, intravenously injected recombinant hACE2 protein (rhACE2) as biological therapeutics has been developed and showed great potential to intercept the entry of virus, limit the progression of infection and reduce lung injury 18,19
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