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Use in the morning for oil control and at night for repair and recovery

PubMed Pairs well with Niacinamide Glabridin Kojic Acid Hydroquinone Alpha-hydroxy acids Salicylic acid Retinoids Avoid combining with High-pH formulations (may reduce stability) Oxidizing agents (benzoyl peroxide may degrade) INGREDIENT DEPIGMENTING AGENT / TYROSINASE INHIBITOR Alpha-Arbutin also known as Alpha-Arbutin, -Arbutin Function May help support skin brightening and even tone through tyrosinase inhibition and melanin synthesis modulation How it works Alpha-arbutin undergoes hydrolysis to release hydroquinone, which research indicates may inhibit tyrosinase enzyme activity and potentially reduce melanin production in melanocytes

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This means that no matter what type of genetic mutations you have (MTHFR included), your body will have no issues in processing them