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In rabbits, the reported IV effective dose was 25 mcg/kg while the subcutaneous dose was 1 mg/kg a 40-fold difference

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This reaction converts the reduced form of glutathione (GSH) into oxidized glutathione (GSSG), which is then reduced back to GSH by glutathione reductase (GR), using electrons from NADPH (Dringen and Arend, 2025)