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This approach was used in a rodent model where the investigators have selectively reduced blood pressure without affecting heart rate and breathing rate by using multi-contact electrodes on cVN (Gierthmuehlen and Plachta 2016)
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In adulthood however, dietary restrictions decreasing IIS may reduce the risk of age-associated pathology like proteotoxicity as recently demonstrated in a mouse model of Alzheimer disease [33]
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