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For example, the deletion of p53 prevents the nuclear accumulation of dipeptidyl peptidase-4 (DPP4), thus facilitates plasma-membrane-associated DPP4-dependent lipid peroxidation, which finally results in ferroptosis
This finding derives from in silico analysis of gene expression databases rather than a single controlled experimental study, and should be interpreted as hypothesis-generating rather than definitive
It also leaves a clear record for the lab's file
Supplementation may help lower this risk
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