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We plan to investigate whether this same brain Rap1 signaling is responsible for other well-documented effects of the drug on the brain." The findings are reported in Science Advances

Patients should report any side effects immediately, especially if they involve the heart, digestive system, or blood sugar

Although initially intended for type 2 diabetes, tirzepatide trials have evidenced considerable weight loss impact because the drug triggers both GLP-1 and GIP receptors that reduce hunger and control blood sugar