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A new glucagon and GLP-1 co-agonist eliminates obesity in rodents
10.1080/03008207.2019.1665035 Summary Keywords knee osteoarthritis, oxidative stress, reactive oxygen species, cartilage, synovitis Citation Liu L, Luo P, Yang M, Wang J, Hou W and Xu P (2022) The role of oxidative stress in the development of knee osteoarthritis: A comprehensive research review
The gene expression changes the peptide triggers may be more important than continuous peptide presence
Upon challenge by oxidants Nrf2 does not undergo ubiquitination and is released from Keap1 as a result of the modification of cysteine residues in Keap1 and/or phosphorylation of Nrf2
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