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"Medications like these lead to weight loss, which helps to improve sleep apnea," explains Brian Wojeck, MD, MPH, an endocrinologist at Yale Medicine in New Haven, Connecticut

SLC19A1, a gene encoding a membrane folate carrier, was reduced in obese WAT and induced global DNA hypermethylation of chemokine C-C motif chemokine ligand 2 (CCL2) that is a key factor in WAT inflammation, 219 resulting in increased CCL2 protein secretion and the development of IR in obese

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For more context, Cymbiotikas article on Understanding How Glutathione Works in Our Body is worth reading