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This could trigger a positive feedback cycle whereby protein aggregates trigger the aggregation of other proteins in a chain reaction that eventually captures elements of the proteostatic mechanisms in place to counteract them

The optimal injection timing for the combination is consistent from week to week, ideally the same day and approximate time each week

Changes in resorufin fluorescence were measured in a 96-well microtiter plates following the protocol outlined in the commercially available Cytochrome P450 2B Fluorescent Detection Kit (CYTO2B

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