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Key findings from the STEP UP study include: The STEP UP trial (Study 8) was a randomized, controlled, phase 3b trial that evaluated the efficacy and safety of once-weekly Wegovy 7.2 mg compared with Wegovy 2.4 mg and placebo, alongside lifestyle interventions (diet and exercise), in 1,407 adults with obesity (BMI 30 kg/m) without type 2 diabetes
Most providers follow a gradual titration schedule: Not everyone needs to reach the maximum dose
Unlike synthetic hormones, many therapeutic peptides work by amplifying or modulating the bodys own natural processes
EBioMedicine 30 , 317325 (2018)
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