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Patients with T2DM experience a significant decline in the incretin function causing delayed and reduced insulin release after glucose administration, impairing glucose tolerance [12,13,14]

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Investigations purport that their combined exposure to research models may yield new insights into the complex interplay of peptide-mediated regulatory mechanisms

Semaglutide is also backstopped by randomized, controlled trial evidence showing that its use reduces the risk of major adverse cardiovascular events, as demonstrated in the SELECT trial