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Neurons are particularly vulnerable to oxidative stress because of their high oxygen demand, abundance of unsaturated lipids and relatively low antioxidant capacity 83

These methods include combined hormonal contraceptives, oral progestins and the progestin injection (Depo Provera), as well as the contraceptive implant (Nexplanon) and levonorgestrel intrauterine device (IUD)

The warning is based on studies in mice and rats, however, and studies in humans have found no increased risk of thyroid cancer