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The analytical evaluation by the Begg & Mazumdar and the Egger tests do not suggest publication bias ( p = 0.472 and p = 0,102, respectively)

Nociceptive pain, arising from actual or imminent tissue injury, encompasses well-defined somatic pain or diffuse visceral discomfort accompanied by autonomic symptoms such as nausea and diaphoresis

This can reduce the chance of stomach and bowel side effects, including yellow stool

BeMediq Why Diet Alone Often Isn't Enough And What GLP-1 Therapy Changes GLP-1 receptor agonists produce up to 15% body weight loss in clinical trials significantly more than diet and exercise alone