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These studies looked at GLP1-RAs in those with obesity and other comorbidities, without T2D, at weight loss doses
Notably, AMPK inhibition abolishes these benefits, confirming that -PAEs protective effects are AMPK-dependent ( Table 1 Multi-targeted mechanisms of hepatoprotection
With dopaminergic drugs: BPC-157s dopamine modulation could potentiate or antagonize therapeutic effects of antipsychotics, ADHD medications, and Parkinsons treatments unpredictably
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