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The two drugs do not have a known direct interaction, meaning that taking one doesnt usually change how the other works in your body
The endocrinologist I have spoken with regularly about this has mentioned that semaglutide is more muscle sparing than Mounjaro, which raises interesting points about how wide this market may be in terms of each modality perhaps retaining a market share for a very specific type of body composition requirement
Doctors typically start patients on a lower dose of both medications and then adjust the dosage based on how well the patient tolerates the treatment
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Endocrinology , 142(12), 51825189.
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