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In general, disordered domains are unsuitable targets for potent peptide binding because of the lack of well-defined binding surfaces, conformational flexibility, and associated entropic penalties 60,61
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Br J Dermatol 155:653656 Read T, Noonan C, David M, Wagels M, Foote M, Schaider H, Soyer HP, Smithers BM (2016) A systematic review of non-surgical treatments for lentigo maligna
While each peptide has been studied for distinct effects, interest has grown around their combined use, often discussed in orthopedic and sports medicine contexts as part of supportive recovery strategies
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