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Through the VEGFR2-Akt-eNOS pathway, it promotes angiogenesis (new blood vessels), ensuring that the metabolically active fibroblasts stimulated by GHK-Cu receive the oxygen and nutrients needed for protein synthesis
GHK-Cu also modulates gene expression through mechanisms that remain incompletely characterized but involve broad transcriptomic changes affecting over 4,000 human genes as identified through Connectivity Map (CMAP) analysis
Its a small chain of amino acids (a nonapeptide) first identified decades ago
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