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Parathyroid hormonerelated peptide 1 (PTHrP-1) promotes chondrocyte proliferation and differentiation and thus has therapeutic value for cartilage repair (Huang et al., 2020)
The antihyperglycaemic effect starts after the first dose and is sustained throughout the once-weekly dosing interval, as a result of the prolonged half-life of 4.7 days
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The digestive symptoms experienced during GLP-1 therapy result from altered gastrointestinal motility and delayed gastric emptying rather than enzyme deficiency
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