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In propensity-matched analyses, semaglutide treatment was associated with lower rates of several cardiovascular outcomes than treatment with metformin, dipeptidyl peptidase-4 (DPP-4) inhibitors, and sodium-glucose cotransporter 2 (SGLT2) inhibitors
Why It Works : Berberine influences gut health and increases GLP-1 production, supporting weight management and blood sugar balance
This separation helps prevent confusion about approved uses and supports compliance with FDA promotional regulations that prohibit manufacturers from marketing drugs for non-approved indications
J., Su, Y
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