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In select cases particularly patients with: Obesity High insulin resistance Very high total daily insulin requirements endocrinologists may consider off-label use with: Continuous glucose monitoring Routine ketone monitoring Strict sick-day protocols Close specialist follow-up But this is not standard therapy

It has not been adequately compared directly with liposomal glutathione

Current clinical guidance and prescribing information do not require a washout period when switching between any GLP-1 receptor agonists, including switches between pure GLP-1 drugs and dual GIP/GLP-1 agonists

S -transferases: an update"