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Individuals with liver disease, elevated liver enzymes, or other hepatic concerns should discuss all supplements, medications, and peptides with their healthcare provider

A suggested mechanism involves prolonged GIPR agonism causing receptor degradation, reducing sustained GIP signalling and, when combined with GLP-1R agonism, causing increased weight loss ( The GLP-1R has itself several LoF variants including R380C, shown by two independent groups to have normal surface expression but reduced affinity for Exenatide (Wootten et al., 2016

Available support services and resources for patients You are not alone on this journey

Well be there to encourage you and keep you motivated