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A 2021 review published in Nutrients found that GLP-1 receptor agonist use was associated with reduced dietary intake of multiple micronutrients including B12, particularly in patients following calorie-restricted eating patterns, supporting the rationale for monitoring B12 status during treatment even in patients without pre-existing deficiency risk factors

Instead, modified activity that avoids aggravating movements while maintaining baseline function typically produces better outcomes

Regular physical activity and keeping track of calories can make a big difference in achieving weight goals

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