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The most frequently reported side effects in Phase 2 trials are gastrointestinal: nausea, vomiting, diarrhoea, and constipation, particularly during dose escalation
Tirzepatide 10 mg and 15 mg demonstrated statistically significant reductions in SBP compared to GLP-1 RA, semaglutide 1 mg (5.3 mmHg and 6.5 mmHg vs 3.6 mmHg, respectively)
Addressing emotional eating patterns, developing coping strategies beyond food, and building sustainable habits are essential components of the GLP-1 journey
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