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The concentration of total GSH was calculated by interpolating the absorbance of the samples on a calibration curve with known concentrations of 0, 1, 5, 10, 15, 20, 40, and 50 mol/L (prepared from a stock solution of 1 mM GSH)
In healthy cells, p53 activation can initiate DNA repair or apoptosis depending on damage severity
*Promotes cell health
The key implication here is that FOXO4-DRI has the potential to develop supportive care protocols to reduce long-term adverse effects of chemotherapy and improve overall quality of life for cancer survivors
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