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This coordinated physiological response reduces hunger, increases fullness, and notably, appears to diminish the cognitive preoccupation with food that characterizes food noise
"Intranasal delivery of biologics to the central nervous system." Advanced Drug Delivery Reviews , 64(7), 614-628
A 2020 study in Frontiers in Endocrinology reviewed how the endocannabinoid system regulates appetite, glucose homeostasis, and energy balance, sometimes in ways that overlap with GLP-1 signaling
