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Once inflammation and oxidative stress start building up and superseding the amount of available antioxidants like glutathione, they can cause damage to cells and the mitochondria inside of cells leading to memory loss, anxiety, depression, joint pain, fatigue, weakness, weight gain, and increased risk of diabetes, heart disease, and cancer
As stimulation increases, so does the braking system
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5.2 Pharmacotherapy Targeting Pathogenesis Alpha-Lipoic Acid Since oxidative stress plays a significant role in the pathogenesis of DPN, attention has been focused on antioxidants such as alpha-lipoic acid (ALA) as potential treatments
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