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Furthermore, the proposed oncogenic role of 4E-BP1 under stress conditions such as hypoxia has only been investigated in vitro , with no supporting data from human tumor tissues or clinical trials

Mitochondrial function Researched for its part in mitochondrial redox reactions and energy output, largely in preclinical and animal models

This review aims to overview the available studies regarding the multiple anti-cancer effects of anti-diabetic drugs discovered in TC as well as to discuss their potential repositioning for TC therapy

Peptides are a lower-potency, higher-uncertainty alternative, not an equivalent substitute