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Peer review Peer review information Nature Communications thanks Zhiyin Song, Sudarshan Rajagopal, and the other anonymous reviewer(s) for their contribution to the peer review of this work

Summary: Macrogol (polyethylene glycol) preparations such as Laxido and Movicol are generally considered the most effective stool softeners for GLP-1 users, as they are well-tolerated for long-term use and particularly suitable for chronic constipation

Thats because the medication reduces your appetite, which helps reduce calorie intake

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