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For a true head-to-head comparison of semaglutide versus tirzepatide, the SURMOUNT-5 trial (Aronne et al., NEJM 2024, NEJMoa2416394) provides a clear advantage for tirzepatide
Safer alternatives for non-injectable weight loss If needles make you anxious and the search for a convenient alternative has you looking for GLP-1 patches, you might want to try these first: Oral GLP-1s: Oral GLP-1 drugs, such as Rybelsus and Wegovy Pill, can be excellent options for patients with needle anxiety
The thyroid cancer warning is more about caution than proven risk
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