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Further studies revealed that a protruding -hairpin structure in ERO1 engages with a hydrophobic pocket on reduced PDIs b domain, thereby leading to preferential oxidation of the C-terminus PDIs a domain (Wang et al., 2009) (Figure 1)
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They should be avoided by people with swallowing difficulties or gastrointestinal strictures
Compared to the control mice, urinary levels of cholic acid, lithocholic acid and -muricholic acid were significantly elevated in mice treated with APAP, while ursodeoxycholic acid and -muricholic acid were significantly decreased
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