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Here is a short list of problems that could be related: obesity diabetes fatigue any psychiatric or neurological problem, difficulty sleeping, muscle tension, or excessive startling any issues with allergies or histamine nausea and vomiting, including but not limited to pregnancy hangriness that is not verifiably due to low blood sugar and resolved by stabilizing blood sugar diarrhea, excessive gastrointestinal transit time heart palpitations, twitches and spasms, chronic pain, tremors high estrogen, low testosterone, any problems that appear as high estrogen or low testosterone but are not accompanied by the expected changes in those hormones petechiae, purpura, cancer, anything resembling hypoxia such as blue hands and feet upon standing any sulfur-related odors such as rotten eggs or matches any form of intolerance to any dietary or supplemental component that contains sulfur anywhere in its structure, like thiamin or lipoic acid or any intolerance to any of the following: fasting, fasting-mimicking diets, ketogenic diets, any kind of catabolic state, B6, calcium, riboflavin, or CoQ10

Repeated temperature cycling accelerates degradation noticeably more than steady storage at any single temperature inside the recommended bands minimise transitions between cold and ambient

This is not specific to B12 but reflects the sensitivity of the gastrointestinal tract in these conditions

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