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K-means clustering of amplicon sequence variant data confirmed that 5-Amino-1MQ treatment generated a distinct cecal microbiome profile from all other treatment groups including diet-switched vehicle controls indicating that NNMT inhibition produces microbiome changes that are separable from those produced by dietary composition alone
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The most common side effects with topical use include mild redness, temporary stinging at application site, and initial purging (worsened appearance before improvement)
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