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However, the SURPASS J-mono trial found that although HbA1c reductions increased with higher tirzepatide doses, differences in weight loss between 10 and 15 mg were modest, which is consistent with our observations [6]

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Diabetic ketoacidosis (DKA) is most commonly associated with type 1 diabetes , though it can occur in type 2 diabetes under certain circumstances

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6ae), and tended to increase energy expenditure, fat oxidation and uncoupling protein-1 (UCP-1) expression without altering locomotor activity (Supplementary Fig

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